Fast, gentle and effective relief. Each 5.4 mL average delivered dose there is 5.4 grams of glycerin. Liquid glycerin is a hyperosmotic laxative that attracts water into the stool and promotes bowel movement.. No-mess applicator is lubricated for easy insertion; has anatomically correct tip; and a collar which limits over-insertion.. Four constipation-relieving suppositories per box.